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[ADMAdda5]microcystin-LR


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  • Norine ID: NOR00136
  • DOI: 10.26097/nor00136
  • Family: microcystin
  • Synonym(s): [ADMAdda5]microcystin-LR;
  • Activity: toxin
  • Category: PK-NRP
  • Formula: C50H74N10O13
  • Monoisotopic mass: 1022.543682504 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 7
  • Monomeric composition :
    1
    D-Ala
    2
    Leu
    3
    D-bMe-Asp
    4
    Arg
    5
    ADMAdda
    6
    D-Glu
    7
    NMe-Dha
  • Graph representation: D-Ala,Leu,D-bMe-Asp,Arg,ADMAdda,D-Glu,NMe-Dha @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Oscillatoria agardhii
  • gram: negative
  • synonyms: Planktothrix agardhii
  • taxid: 1160 (view NCBI taxonomy browser)

  • Nostoc
  • gram: negative
  • synonyms: Amorphonostoc
  • taxid: 1177 (view NCBI taxonomy browser)

  • Links between organisms producing the [ADMAdda5]microcystin-LR: Oscillatoria agardhii, Nostoc
  • Structures of three new cyclic heptapeptide hepatotoxins produced by the cyanobacterium (blue-green alga) Nostoc sp. strain 152
    Sivonen K, Namikoshi M, Carmichael WW, Rinehart KL, Sakai R, The Journal of organic chemistry , 1990, 55 (25), pp. 6135-6139
  • [ADMAdda5]-microcystins in Planktothrix agardhii strain PH-123 (cyanobacteria)--importance for monitoring of microcystins in the environment
    Carmichael WW, Rinehart KL, Laub J, Henriksen P, Brittain SM, Wang J, Moestrup O, Environmental toxicology , 2002, 17(4):351-7.
    DOI: 10.1002/tox.10042
    pubMed: 12203956


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