Peptide

Norine ID: NOR00659
DOI: 10.26097/nor00659
Family: montanastatin
Synonym(s): montanastatin;
Activity: antitumor, toxin
Category: peptide
Formula: C36H60N4O12
Monoisotopic mass: 740.420773404 g/mol
Comment: Montanastatin is a putative NRPS product (no synthetase genes identified).
Source: norine
Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
Entry information:
- status: putative - change status to non-NRP (Norine validators only)

Type: cyclic
Number of monomers: 8
Smiles: CC1C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)OC(C(=O)NC(C(=O)O1)C(C)C)C(C)C)C(C)C)C)C(C)C)C(C)C)C(C)C
Graph inference:

Monomeric composition :

D-Hiv

D-Val

Lac

Val

D-Hiv

D-Val

Lac

Val

Graph representation: D-Hiv,D-Val,Lac,Val,D-Hiv,D-Val,Lac,Val @1,7 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @0,6
Atomic structure:

vizualisation:

gram: positive
synonyms: Streptomyces anulatus,Streptomyces fluorescens,Streptomyces citreofluorescens,Actinomyces fluorescens,Actinomyces citreofluorescens,Actinomyces annulatus,Actinomyces Streptothrix annulatus
taxid: 1892 (view NCBI taxonomy browser)

Links between organisms producing the montanastatin: Streptomyces chrysomallus

Antineoplastic agents. Part 409: Isolation and structure of montanastatin from a terrestrial actinomycete.
Pettit GR, Doubek DL, Schmidt JM, Herald DL, Tan R, Melody N, Kielty JM, Pettit RK, Tucker BE, Mallavia LP, Bioorganic and medicinal chemistry , 1999, May,7(5):895-9.
DOI: 10.1016/s0968-0896(99)00024-3
pubMed: 10400343

Norine