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bacillomycin L-1


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  • Norine ID: NOR00223
  • DOI: 10.26097/nor00223
  • Family: iturin
  • Synonym(s): bacillomycin L-1;
  • Activity: surfactant, antimicrobial
  • Category: lipopeptide
  • Formula: C46H72N10O16
  • Monoisotopic mass: 1020.512776306 g/mol
  • Comment: C14 and C15 beta-amino acids were the major components with a lower percentage of C16 components.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 8
  • Monomeric composition :
    1
    C14:0-NH2(3)
    2
    Asn
    3
    D-Tyr
    4
    D-Asn
    5
    Ser
    6
    Glu
    7
    D-Ser
    8
    Thr
  • Graph representation: C14:0-NH2(3),Asn,D-Tyr,D-Asn,Ser,Glu,D-Ser,Thr @1,7 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @0,6

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Bacillus subtilis
  • gram: positive
  • synonyms: Bacillus uniflagellatus,Bacillus natto,Bacillus globigii,Vibrio subtilis
  • taxid: 1423 (view NCBI taxonomy browser)

  • Links between organisms producing the bacillomycin L-1: Bacillus subtilis
  • Structures of bacillomycin D and bacillomycin L peptidolipid antibiotics from Bacillus subtilis
    Peypoux F, Das BC, Michel G, Besson F, Pommier MT, Delcambe L, The Journal of antibiotics , 1984, Dec,37(12):1600-4.
    DOI: 10.7164/antibiotics.37.1600
    pubMed: 6441791
  • NMR structure determination of a synthetic analogue of bacillomycin Lc reveals the strategic role of L-Asn1 in the natural iturinic antibiotics
    Besson F, Volpon L, Tsan P, Majer Z, Vass E, Hollosi M, Noguera V, Lancelin JM, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy , 2007, Aug,67(5):1374-81.
    DOI: 10.1016/j.saa.2006.10.027
    pubMed: 17129757
  • Genetic analysis of the biosynthesis of non-ribosomal peptide- and polyketide-like antibiotics, iron uptake and biofilm formation by Bacillus subtilis A1/3
    Vater J, Franke P, Leenders F, Grammel N, Hofemeister J, Conrad B, Adler B, Hofemeister B, Feesche J, Kucheryava N, Steinborn G, Zwintscher A, Hitzeroth G, Molecular genetics and genomics , 2004, Nov,272(4):363-78.
    DOI: 10.1007/s00438-004-1056-y
    pubMed: 15480790


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