obyanamide
- Norine ID: NOR00440
- DOI: 10.26097/nor00440
- Family: obyanamide
- Synonym(s): obyanamide;
- Activity: antitumor
- Category: peptide
- Formula: C30H41N5O6S
- Monoisotopic mass: 599.277754769 g/mol
- Comment: Obyanamide is a putative NRPS product (no synthetase genes identified).
- Source: norine
- Contributor (creation): Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: cyclic
- Number of monomers: 5
- Smiles: CCC3CC(=O)OC(C)C(=O)N(C)C(C(C)C)C(=O)N(C)C(Cc1ccccc1)C(=O)NC(C)c2nc(cs2)C(=O)N3
- Graph inference:
- Monomeric composition :
1 Lac 2 NMe-Val 3 NMe-Phe 4 Ala-Thz 5 C5:0-NH2(3) - Graph representation: Lac,NMe-Val,NMe-Phe,Ala-Thz,C5:0-NH2(3) @1,4 @0,2 @1,3 @2,4 @0,3
- Atomic structure:
- Lyngbya confervoides
- taxid: 207921 (view NCBI taxonomy browser)
- Links between organisms producing the obyanamide: Lyngbya confervoides
- Isolation and structure determination of obyanamide, a novel cytotoxic cyclic depsipeptide from the marine cyanobacterium Lyngbya confervoides
Moore RE, Paul VJ, Williams PG, Yoshida WY, Journal of natural products , 2002, Jan,65(1):29-31.
DOI: 10.1021/np0102253
pubMed: 11809060
- Total synthesis and reassignment of stereochemistry of obyanamide
Zhanga W, Maa ZH, Meia D, Lia CX, Zhanga XL, Li YX, Tetrahedron , 2006, Volume 62, Issue 42, 16 October 2006, Pages 9966-9972
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