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phakellistatin 6


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  • Norine ID: NOR00528
  • DOI: 10.26097/nor00528
  • Family: phakellistatin
  • Synonym(s): phakellistatin 6;
  • Activity: antitumor
  • Category: peptide
  • Formula: C47H62N8O7
  • Monoisotopic mass: 850.474146378 g/mol
  • Comment: Phakellistatins are putative NRPS products (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 7
  • Monomeric composition :
    1
    Pro
    2
    Phe
    3
    Pro
    4
    Trp
    5
    Leu
    6
    Pro
    7
    Ile
  • Graph representation: Pro,Phe,Pro,Trp,Leu,Pro,Ile @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Phakellia sp.

  • Links between organisms producing the phakellistatin 6: Phakellia sp.
  • Antineoplastic agents 323. Isolation and structure of phakellistatin 6 from a chuuk archipelago marine sponge
    Pettit GR, Cerny RL, Chapuis JC, Cichacz Z, Williams MD, Xu JP, Bioorganic and medicinal chemistry letters , 1994, 4 (22), pp. 2677-2682


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