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methylbalhimycin


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  • Norine ID: NOR00709
  • DOI: 10.26097/nor00709
  • Family: balhimycin
  • Synonym(s): methylbalhimycin;
  • Activity: antimicrobial
  • Category: glycopeptide
  • Formula: C67H75Cl2N9O24
  • Monoisotopic mass: 1459.430199793 g/mol
  • Comment: Two bonds of the central Hpg are due to oxidative ring closure.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: other
  • Number of monomers: 9
  • Smiles: C[C@H]1C(=O)[C@@](C[C@@H](O1)O[C@H]2[C@H]3C(=O)N[C@@H](C4=CC(=CC(=C4C5=C(C=CC(=C5)[C@H](C(=O)N3)NC(=O)[C@H]6C7=CC(=C(C(=C7)OC8=C(C=C(C=C8)[C@H]([C@H](C(=O)N[C@H](C(=O)N6)CC(=O)N)NC(=O)[C@@H](CC(C)C)N(C)C)O)Cl)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)OC1=C(C=C2C=C1)Cl)O)O)O)C(=O)O)(C)N

  • Graph inference:



  • Monomeric composition :
    1
    Asn
    2
    bOH-Cl-Tyr
    3
    NdMe-Leu
    4
    Hpg
    5
    D-Glc
    6
    bOH-Cl-Tyr
    7
    4oxo-Van
    8
    Dhpg
    9
    Hpg
  • Graph representation: Asn,bOH-Cl-Tyr,NdMe-Leu,Hpg,D-Glc,bOH-Cl-Tyr,4oxo-Van,Dhpg,Hpg @1,3 @0,3,2 @1 @1,0,4,5,8 @3 @3,7,6,8 @5 @8,5 @3,7,5

  • Atomic structure:
    • Chemical structure
    rBAN vizualisation:
  • Amycolatopsis sp.
  • gram: positive
  • taxid: 37632 (view NCBI taxonomy browser)

  • Links between organisms producing the methylbalhimycin: Amycolatopsis sp.
  • Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics
    Nicolaou KC, Boddy CN, Brase S, Winssinger N, Angewandte Chemie , 1999, Aug,38(15):2096-2152.
    pubMed: 10425471


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