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cupolamide A


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  • Norine ID: NOR00574
  • DOI: 10.26097/nor00574
  • Family: cupolamide
  • Synonym(s): cupolamide A;
  • Activity: toxin
  • Category: peptide
  • Formula: C42H68N11O11
  • Monoisotopic mass: 902.509977073 g/mol
  • Comment: Cupolamide A is a putative NRPS product (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 8
  • Monomeric composition :
    1
    Val
    2
    D-Ser
    3
    D-Leu
    4
    D-Har
    5
    Val
    6
    4OH-Pro
    7
    Dab
    8
    pOH-Bz
  • Graph representation: Val,D-Ser,D-Leu,D-Har,Val,4OH-Pro,Dab,pOH-Bz @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5,7 @6

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Theonella cupola
  • taxid: 1336890 (view NCBI taxonomy browser)

  • Links between organisms producing the cupolamide A: Theonella cupola
  • Cupolamide A: A Cytotoxic Cyclic Heptapeptide from Two Samples of the Sponge Theonella cupola
    Scheuer PJ, Nakao Y, Yoshida WY, Tanaka J, Higa T, Bonnington LS, Kimura J, Yoshimura Y, Journal of Organic Chemistry , 1997, 62 (22), pp. 7765-7767


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