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apicidin C


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  • Norine ID: NOR01112
  • DOI: 10.26097/nor01112
  • Family: apicidin
  • Synonym(s): apicidin C;
  • Activity: antitumor, toxin
  • Category: peptide
  • Formula: C33H47N5O6
  • Monoisotopic mass: 609.352634261 g/mol
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 4
  • Monomeric composition :
    1
    C10:0-NH2(2)-oxo(8)
    2
    D-Hpr
    3
    Val
    4
    OMe-Trp
  • Graph representation: C10:0-NH2(2)-oxo(8),D-Hpr,Val,OMe-Trp @1,3 @0,2 @1,3 @0,2

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Fusarium
  • gram:
  • synonyms:
  • taxid: 5506 (view NCBI taxonomy browser)

  • Links between organisms producing the apicidin C: Fusarium
  • Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities
    Singh SB, Zink DL, Liesch JM, Mosley RT, Dombrowski AW, Bills GF, Darkin-Rattray SJ, Schmatz DM, Goetz MA, The Journal of organic chemistry , 2002, Feb 8,67(3):815-25.
    DOI: 10.1021/jo016088w
    pubMed: 11856024


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