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M43A


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  • Norine ID: NOR00694
  • DOI: 10.26097/nor00694
  • Family: M43
  • Synonym(s): M43A;
  • Activity: antimicrobial
  • Category: glycopeptide
  • Comment: Two bonds of the central Hpg are due to oxidative ring closure.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2007-02-12 by Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: other
  • Number of monomers: 9
  • Monomeric composition :
    1
    Asn
    2
    bOH-Cl-Tyr
    3
    NtMe-Leu
    4
    Hpg
    5
    D-Glc
    6
    Van
    7
    bOH-Cl-Tyr
    8
    Dhpg
    9
    Hpg
  • Graph representation: Asn,bOH-Cl-Tyr,NtMe-Leu,Hpg,D-Glc,Van,bOH-Cl-Tyr,Dhpg,Hpg @1,3 @0,2,3 @1 @1,0,4,6,8 @3,5 @4 @3,7,8 @6,8 @3,7,6

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Nocardia orientalis
  • gram: positive
  • synonyms: Amycolatopsis orientalis,Streptomyces orientalis,Amycolatopsis orientalis orientalis
  • taxid: 31958 (view NCBI taxonomy browser)

  • Links between organisms producing the M43A: Nocardia orientalis
  • M43 antibiotics: Methylated vancomycins and unrearranged CDP-I analogues
    Nagarajan R, Merkel KE, Michel KH, Higgins Jr. HM, Hoehn MM, Hunt AH, Jones ND, Swartzendruber JK, Journal of the American Chemical Society , 1988, 110 (23), pp. 7896-7897


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